carvedilol이 또 vasodilation이 없는 건 아닐 지도용...

Carvedilol and labetalol appear to cause vasodilation through alpha(1)-receptor blockade;

The vasodilatory beta-blockers - PubMed (nih.gov)

In patients with obstructive HCM and symptoms* attributable to LVOTO, nonvasodilating beta-blockers, titrated to effectiveness or maximally tolerated doses, are recommended

Beta-blockers were the first studied medication for treatment of dynamic outflow tract obstruction and are generally considered the first-line agent for most patients with obstructive HCM. Medications should be titrated to a dose where there is symptom benefit but not declare failure of beta-blockade until there is demonstrated physiologic evidence of beta-blockade (ie, sup- pression of resting heart rate).1–3

이렇게 미국심장학회에 나와있기는 한데말이죠

뇌피셜로 생각하면 BB를 사용하는데 그 중 non-vasodilating이 더 좋다는 의미 아닐까요?

Nadolol, metoprolol succinate가 nonvasodilating beta blocker라고 합니다

Medicines can help reduce how strongly the heart muscle squeezes and slow the heart rate. That way, the heart can pump blood better. Medicines to treat hypertrophic cardiomyopathy and its symptoms might include:

• Beta blockers such as metoprolol (Lopressor, Toprol-XL), propranolol (Inderal LA, Innopran XL) or atenolol (Tenormin).

• Calcium channel blockers such as verapamil (Verelan) or diltiazem (Cardizem, Tiazac, others).

https://www.mayoclinic.org/diseases-conditions/hypertrophic-cardiomyopathy/diagnosis-treatment/drc-20350204#:~:text=Beta%20blockers%20such%20as%20metoprolol,)%20or%20atenolol%20(Tenormin).